(Voet & Voet Chapter 23)
1). How is lipid (triglycerides and phospholipids) digested, absorbed, and transported? What are the major enzymes involved?
b. Where does the £] oxidation of FA take place? How is the acyl CoA transported to this oxidation sites (via what kind of carrier)?
c. What is the relationship between FA £] oxidation and oxidative phosphorylation?
d.How is the odd chain FA oxidized? What are the major enzymes for the final C3 oxidation and what are the cofactors for these enzymes?
e. What is the significance of peroxisomal £] oxidation? What are the differences between peroxisomal and mitochondria FA oxidation?
f. How is the ketone body (what kind of compounds?) generated? What is its physiological significance?
b. Where does FA synthesis take place? How is the acetyl CoA transported for the FA synthesis?
5). Which enzyme is the key point for the regulation of cholesterol synthesis? Is it cAMP dependent? What is the key intermediate?
6). Arachidonate is synthesized from which essential FA? What kinds of biological active compounds are produced from arachidonate by cyclic and linear pathway, respectively?
7). What is the difference between
and sphingolipid? How many kinds of sphingolipids are found in human
Last modified on 1999.3.22 by K.-J.